Equine performance.

Topical carnosine for animal use, featured here for equine performance and care.

Performance horse in equine carnosine research section

EQUINEFORTIGO

THE HORSE GAVE RESEARCHERS A WAY TO LOOK INSIDE THE MUSCLE.

A controlled equine study directly measured muscle carnosine after topical application.

Transdermal delivery of carnosine into equine skeletal muscle

Journal
Comparative Exercise Physiology
Year
2021
Design
Randomized, placebo-controlled crossover study
Subjects
10 Thoroughbred racehorses
Application area
Middle gluteal muscle
Measurement
Muscle biopsies
  1. BASELINETopical carnosine or placebo applied
  2. 30 MINMuscle biopsy
  3. 60 MINMuscle biopsy
  4. 120 MINMuscle biopsy
≈ +35%at 30 minutes
≈ +46%at 60 minutes

Intramuscular carnosine concentration was higher after carnosine application than after placebo at 30 and 60 minutes.

At 120 minutes, the difference from placebo was not statistically significant.

PLACEBO REFERENCE≈ +35%≈ +46%NOT SIGNIFICANT0 MIN30 MIN60 MIN120 MIN

Conceptual view of reported relative differences. Not raw concentration data. 120-min position is illustrative only.

WHAT DID THEY ACTUALLY PROVE?

The study provides direct evidence that topical application using the tested transdermal system increased measured carnosine concentration in equine skeletal muscle within 60 minutes.

WHAT IT DID NOT TEST

The study did not directly measure racing speed, competition results, athletic performance, soreness, or recovery outcomes.

WHY THIS STUDY MATTERS

Most topical performance claims rely on how a product feels on the skin. This study went further: researchers took muscle biopsies and measured carnosine inside the muscle itself.

That makes the equine study an important piece of evidence in understanding topical carnosine delivery.

HORSES & MUSCLE CARNOSINE

Equine skeletal muscle contains substantial amounts of carnosine, with higher concentrations reported in fast-twitch muscle fibers involved in high-intensity activity.

Sewell DA, Harris RC, Marlin DJ, Dunnett M. “Estimation of the carnosine content of different fibre types in the middle gluteal muscle of the thoroughbred horse.” The Journal of Physiology. 1992.

VIEW SOURCE ↗

MEET FORTIGO.

A topical carnosine gel developed for equine use.

  • TOPICAL
  • EQUINE-SPECIFIC
  • CARNOSINE-BASED
Fortigo Animal Health topical carnosine gel bottle
  • RACING
  • ENDURANCE
  • SHOW JUMPING
  • DRESSAGE
  • BARREL RACING
  • WORKING HORSES

Dieter BP, Macias CJ, Sharpe TJ, et al. “Transdermal delivery of carnosine into equine skeletal muscle.” Comparative Exercise Physiology. 2021;17(5):429–434. DOI: 10.3920/CEP200077

VIEW PUBLISHED STUDY ↗

THE EQUINE STUDY ANSWERED ONE QUESTION: CAN TOPICAL CARNOSINE REACH MUSCLE?

THE NEXT QUESTION WAS DIFFERENT: COULD TOPICAL CARNOSINE AFFECT HUMAN PERFORMANCE?

FORTIGO. FOR ANIMALS.

FOR ANIMALS

FORTIGO

Topical carnosine gel for animal use.

  • Targeted topical application
  • Massage in thoroughly per product directions
  • Daily care • Before activity • After work
237 mL946 mL
Fortigo Animal Health topical carnosine gel bottle

FOR ANIMAL TOPICAL USE ONLY • NOT FOR USE ON HUMANS

GET FORTIGO →

Simple to apply.
Built into the routine.

Choose the product that matches who you're applying it to.

For animal use

How to use Fortigo

  1. 01

    Apply

    Apply Fortigo to the area you want to target.

  2. 02

    Massage

    Massage in thoroughly.

  3. 03

    Use as directed

    Use according to Fortigo product directions and appropriate animal-care guidance.

Daily care • Before activity • After work

Targeted topical application

Apply only according to Fortigo product directions and appropriate animal-care guidance.

Horse • Canine

  • Fortigo Animal Health
  • Topical
  • 237 mL
  • 946 mL

For animal topical use only • Not for use on humans

Application is simple.
The next question is why topical?

Questions about carnosine?

Start with the questions people ask before they understand the science, the products, or the difference between human and animal use.

Animal / Fortigo

Fortigo Animal Health is a topical carnosine-based product for animal use. It is not for use on humans.

Yes. Fortigo is used in the equine category and is the animal-use product featured throughout the horse sections of The Carnosine.

Fortigo is an animal-use topical product. Canine use should follow the current Fortigo product directions and appropriate animal-care guidance. The Carnosine does not claim that horse research automatically proves the same effects in dogs.

The Fortigo products currently featured on The Carnosine are 237 mL and 946 mL.

Apply Fortigo to the area you want to target and massage in thoroughly, following the current product directions and appropriate animal-care guidance.

Current product guidance supports use as part of daily care, before activity or after work. Follow the current Fortigo label for the most accurate instructions.

No. Fortigo is for animal topical use only and is not for use on humans.

Yes. A peer-reviewed 2021 equine study measured intramuscular carnosine after topical application and reported higher muscle carnosine concentrations at 30 and 60 minutes compared with placebo.

View source ↗

You've seen the science.
You've seen the products.
Now choose your performance world.

Performance starts inside the muscle.

Choose the product built for your performance world.

Equine

Fortigo Animal Health

Topical carnosine for animal use, featured here for equine performance and care.

Fortigo Animal Health topical carnosine gel bottle237 mL · 946 mL

Choose Fortigo size

View equine science

For animal topical use onlyNot for use on humans

Research-led.
Application-focused.
Claims kept in context.

One molecule.
Three performance worlds.
One question: what could carnosine mean for your routine?

Explore. Understand. Choose.

THECARNOSINETRYCARNOSINE.COMProduct information should always be checked against the current manufacturer label and directions.

TALK TO US ABOUT EQUINE USE

Questions about Fortigo or the equine research? Send us a message.